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Tag: P-gp inhibition

Colchicine and Macrolides: Managing Toxicity from P‑gp and CYP3A4 Inhibition
Pharmacy

Colchicine and Macrolides: Managing Toxicity from P‑gp and CYP3A4 Inhibition

A deep dive into why colchicine and macrolide antibiotics can be lethal together, how CYP3A4 and P‑gp inhibition raise toxicity, and practical steps to keep patients safe.

  • Oct, 25 2025
  • 3

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